GLP-1 medications like semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) have fast become some of the most recognizable and popular drugs in the world. Recent research now shows that a sizable number of Americans have been taking GLP-1s off-label.

Scientists at New York University and others examined the medical records of Americans across the country. Since 2021, they found that at least 1.1 million Americans were prescribed a GLP-1 without having an FDA-approved indication for its use, such as obesity or type 2 diabetes. Though some people may be taking these drugs off-label for valid reasons, we’re largely in the…

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